Molecular Pathology You are here:HomeOur ServicesMolecular Pathology St Vincent's Pathology offers a comprehensive suite of predictive and prognostic biomarkers for solid tumours and haematologic malignancies, utilising next-generation sequencing on the Genexus platform and traditional cytogenetic techniques. Karyotyping as well as FISH for haematological malignancies and soft tissue tumours are available through the Victorian Cancer Cytogenetics Service. Our solid tumour test menu covers all MBS-rebatable gene testing for lung cancer, colorectal cancer and melanoma as well as a number of other MBS-rebatable targets in brain tumours, breast and salivary gland. We welcome collaboration with researchers and clinical trials. Click here for our Molecular Oncology test request form Next Generation Sequencing panels: Oncomine Precision Assay (OPA) 45 gene NGS DNA panel (AKT1, AKT2, AKT3, ALK, AR, ARAF, BRAF, CDK4, CDKN2A, CHEK2, CTNNB1, EGFR, ERBB2, ERBB3, ERBB4, ESR1, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MAP2K1, MAP2K2, MET, MTOR, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA, PTEN, RAF1, RET, ROS1, SMO and TP53) - choose this panel for point mutations and deletions/insertions, does not detect fusions Oncomine Precision Assay (OPA) NGS RNA fusion panel (ALK, AR, BRAF, ESR1, FGFR1, FGFR2, FGFR3, MET, NRG1, NTRK1, NTRK2, NTRK3, NUTM1, RET, ROS1, RSPO2, RSPO3) - choose this panel for MET exon 14 skipping and gene fusions Fluorescence in situ hybridisation (FISH): ALK ROS1 RET 1p/19q EGFR amplification HER2 amplification Methylation testing by High Resolution Melting: MGMT MLH1 For any enquiries regarding solid tumour molecular testing, please contact the team: molecular@svha.org.au. Molecular Lead A/Prof Penny McKelvie Ph: +61 3 9231 4558 Email: Penny.McKelvie@svha.org.au Supervising Clinical Scientist Dr Asif Alam, PhD Ph: +61 3 9231 4561 Email: Asif.Alam@svha.org.au