Molecular Pathology

St Vincent's Pathology offers a comprehensive suite of predictive and prognostic biomarkers for solid tumours and haematologic malignancies, utilising next-generation sequencing on the Ion Torrent platform and traditional cytogenetic techniques.

Karyotyping as well as FISH for haematological malignancies and soft tissue tumours are available through the Victorian Cancer Cytogenetics Service.

Our solid tumour test menu covers all MBS-rebatable gene testing for lung cancer, colorectal cancer, melanoma and brain tumours as well as a number of other gene targets of clinical interest.

We welcome collaboration with researchers and clinical trials.


Click here for our Molecular Oncology test request form

 

Fast Mutation Test:

  • Idylla EGFR Mutation Test

Next Generation Sequencing panels:

  • 22 gene NGS DNA panel (AKT1, ALK, BRAF, CTNNB1, DDR2, EGFR, ERBB2, ERBB4, FBXW7, FGFR1, FGFR2, FGFR3, KRAS, MAP2K1, MET, NOTCH1, NRAS, PIK3CA, PTEN, SMAD4, STK11 and TP53)
  • 50 gene NGS DNA panel (ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZF2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, and VHL)
  • NGS Lung RNA fusion panel (ALK, NTRK1, RET and ROS1)
  • NGS thyroid DNA panel (AKT1, BRAF, CTNNB1, EIF1AX, GNAS, HRAS, KRAS, NRAS, PIK3CA, PTEN, RET, TERT, TP53 and TSHR)
  • NGS thyroid RNA fusion panel (ALK, BRAF, NTRK1, NTRK3, MAML2, PPARG, RET and THADA)  

Fluorescence in situ hybridisation (FISH):

  • ALK
  • ROS1
  • RET
  • 1p/19q
  • EGFR amplification
  • HER2 amplification

For any enquiries regarding solid tumour molecular testing, please contact the team: molecular@svha.org.au.

Supervising Clinical Scientist

Dr Hongdo Do, Phd

Ph: +61 3 9231 4561

Supervising Pathologist

A/Prof. Trishe Y-M Leong